動(dòng)物步態(tài)分析系統(tǒng)是一個(gè)完整的定量評(píng)估鼠類模型中動(dòng)物腳步和步態(tài)的工具。步態(tài)分析系統(tǒng)的核心部件是步行臺(tái)老鼠可以從步行臺(tái)的一端行走到另一端。該系統(tǒng)采用腳印光亮折射技術(shù)通過置于步行臺(tái)下方的高速攝像機(jī)捕獲真正的腳印。該技術(shù)還能夠探測(cè)到腳步壓力差異這是動(dòng)物行走時(shí)體重在其四個(gè)腳爪上分布不同的結(jié)果。

動(dòng)物步態(tài)分析系統(tǒng)為了獲得自然步態(tài)對(duì)動(dòng)物不采取任何強(qiáng)迫措施。由于行走速度是步態(tài)分析的一個(gè)重要參數(shù)因此該系統(tǒng)也能測(cè)定行走速度并用于數(shù)據(jù)選擇和數(shù)據(jù)分析中。不像其他步態(tài)分析方法該系統(tǒng)不需要任何外部標(biāo)記也不需要修剪腳指甲及在腳爪上蘸取墨汁更不需要明亮充足的光線。

腳印光亮折射技術(shù)

由發(fā)光二極管發(fā)出的光散射到玻璃板內(nèi)光線在玻璃板內(nèi)反射。只有當(dāng)動(dòng)物和玻璃板接觸時(shí)該區(qū)域內(nèi)的光線將朝反的方向折射。典型接觸區(qū)域是動(dòng)物腳爪也可能是尾巴或身體的其他部位。高速攝像機(jī)(100 Hz) 置于玻璃板下方捕獲這些光亮區(qū)域并將信號(hào)發(fā)送到運(yùn)行動(dòng)物步態(tài)分析系統(tǒng)的計(jì)算機(jī)中。步行臺(tái)頂端有一個(gè)頂蓋它產(chǎn)生紅色背景這樣可以使動(dòng)物軀體輪廓影印可視化。

足印自動(dòng)分類技術(shù)新版動(dòng)物步態(tài)分析系統(tǒng)8.1增加了全新的足印自動(dòng)分類技術(shù)該技術(shù)的應(yīng)用使得系統(tǒng)能自動(dòng)地分類足跡為左前、左后、右前、右后。這個(gè)新的功能不僅快速可靠而且節(jié)約研究人員的時(shí)間和精力。如果系統(tǒng)發(fā)現(xiàn)足跡不能識(shí)別例如動(dòng)物將鼻子貼在地板上系統(tǒng)會(huì)自動(dòng)提示手動(dòng)分配正確的標(biāo)簽或直接拋棄足跡。

主要應(yīng)用領(lǐng)域 

動(dòng)物步態(tài)分析系統(tǒng)可用于評(píng)價(jià)神經(jīng)創(chuàng)傷、神經(jīng)性、神經(jīng)疾病、以及疼痛癥狀群的動(dòng)物模型。該系統(tǒng)應(yīng)用范圍包括脊索損傷、神經(jīng)性疼痛、關(guān)節(jié)炎、中風(fēng)、帕金森病、運(yùn)動(dòng)失調(diào)、腦損傷、外周神經(jīng)損傷等疾病的研究。通過步態(tài)分析了解神經(jīng)源性疾病發(fā)展過程、評(píng)價(jià)治療方法的效果和篩選治療藥物。例如帕金森氏癥導(dǎo)致肢體動(dòng)作僵硬和協(xié)調(diào)性降低。步態(tài)分析系統(tǒng)通過測(cè)量動(dòng)物模型中的腳間距離、擺動(dòng)時(shí)相、支撐方式和正常步序比等參數(shù)評(píng)估運(yùn)動(dòng)協(xié)調(diào)性。

動(dòng)物步態(tài)分析系統(tǒng)的軟件可以處理視頻數(shù)據(jù)。依據(jù)每個(gè)腳步的尺寸、位置、移步動(dòng)態(tài)和壓力計(jì)算很多參數(shù)用于定性和定量分析腳步和步態(tài)。

主要測(cè)試參數(shù)

空間參數(shù)
· 步距
· 跨步長(zhǎng)度
· 步寬
· 坐骨神經(jīng)功能指數(shù)足印長(zhǎng)度
· 步態(tài)角度
· 坐骨神經(jīng)功能指數(shù)中趾延展度
· 坐骨神經(jīng)功能指數(shù)腳趾延展度

時(shí)間參數(shù)
· 站立期時(shí)間長(zhǎng)度
· 擺蕩期時(shí)間長(zhǎng)度
· 雙足站立期長(zhǎng)度
· 步行速度

關(guān)節(jié)參數(shù)
· 最初接觸（IC）
· 站立中間期（MST）
· 擺蕩前期（PS）
· 擺蕩中期（MSW）

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