傳統(tǒng)動物心電圖測量分析采用體表方式雖操作簡單但是存在測量位置影響大、測量精度不高等局限性而心外膜表面電極測量心電圖操作極為復(fù)雜且創(chuàng)傷性大實驗中較少采用。為解決這一難題Scisence 提供微創(chuàng)的多電極電生理導(dǎo)管設(shè)計使研究者能夠?qū)ι镫娫谡麄€心臟的擴散過程進行更為深入的測量和分析。

電生理導(dǎo)管系統(tǒng)由八電極電生理導(dǎo)管、電極分配盒及第三方生物電放大器及刺激器組成。

工作原理八電極電生理導(dǎo)管上的每對電極均獨立受控于電極分配盒電極分配盒通過 2mm 針式連接線與第三方生物電放大器或刺激器相連通過采集對應(yīng)的電極對引導(dǎo)的電信號數(shù)據(jù)。八電極電生理導(dǎo)管可用于心臟起搏電信號記錄進而用于心臟電生理的各方面研究。

電生理導(dǎo)管工作原理圖

心臟電生理導(dǎo)管需要插入大鼠、小鼠等動物的心臟內(nèi)部測量和紀錄心房及心室的電生理信號傳導(dǎo)時間、不應(yīng)期、希氏束電位、竇房結(jié)和房室結(jié)功能、心律失常的誘導(dǎo)。 

LabScribe 心電分析模塊

5. 可輕松提取源數(shù)據(jù)或平均數(shù)據(jù)作為圖片或文本導(dǎo)出；

6. 可選 ASCII 文本導(dǎo)入模塊將其他第三方設(shè)備采集的 ECG 數(shù)據(jù)導(dǎo)入本軟件進行分析；

LabScribe 進行心電分析

相關(guān)文獻

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8. Benito B, et. al. “Cardiac arrhythmogenic remodeling in a rat model of long-term intensive exercise training." Circulation. 2011 Jan 4; 123(1)13-22
9. Prestia KA, et al. “Increased Cell-Cell Coupling Increases Infarct Size and Does not Decrease Incidence of Ventricular Tachycardia in Mice." Front Physiol. 2011 Jan 31; 2(1)1-7
10. Aubin MC, et al. “A high-fat diet increases risk of ventricular arrhythmia in female ratsenhanced arrhythmic risk in the absence of obesity or hyperlipidemia." J Appl Physiol. 2010 Feb; 108933-940
11. Lu Y, et al. “MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation." Circulation. 2010 Dec; 122(23)2378-87
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